PHARMACEUTICAL INDUSTRY :
R&D Analytical Laboratory Improvement
  Client:   A major consumer pharmaceutical developer, manufacturer and supplier, with trusted and popular brands. The client supplies products in multiple dosage forms, with total global revenues exceeding $1 billion annually.
     
  Problem:   The firm was resource-constrained in its R&D analytical laboratories. This created a backlog of testing and impacted responsiveness to total business needs. Methods development and validation processes were not being properly supported and scientific staff lacked necessary skills. The firm needed to complete process validations and product transfers for new product launches.
     
  Approach:   The client is now consistently managing the volume and diversity of laboratory work, and has successfully met both internal corporate and external FDA audits. Tunnell has assisted the client on the many critical fronts essential for success: production transfer, scale-up, new product launches, methods development and validation, and analytical testing services.
     
  Results:   Tunnell Consulting entered into an ongoing long-term partnership with the client, already lasting several years, and was ultimately selected as the client's sole supplier of outsourced analytical and validations services. We provided the following:
  • TC assigned high-caliber, experienced scientists to develop and validate methods, address routine testing requirements, and relieve backlogs
  • TC scientists became qualified on client SOPs, lab protocols, data formats, data systems, policies and procedures
  • TC scientists organized, planned, and supervised work teams of analytical chemists, working at client facilities and on client equipment, consistent with cGMP standards
  • TC scientists performed analytical testing across multiple consumer products and dosage forms
  • TC project managers organized data, developed reports, and facilitated the report review and approval process
  • TC provided expert resources to support both routine R&D laboratory testing and clinical/regulatory submissions
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